Research workbench

Crystal structure of a putative macrophage growth locus, subunit a from francisella tularensis schu S4

Analyse Crystal structure of a putative macrophage growth locus, subunit a from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4OMV
Type: protein
Length: 392 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Macrophage growth locus, subunit a
UniProt: Q5NFG1
Pockets: 7 · best druggability 0.69

Structure

x-ray diffraction · 2 distinct chains · 61% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Macrophage growth locus, subunit a	protein	194	61% helix, 8% strand	Q5NFG1
B	Macrophage growth locus, subunit a	protein	198	61% helix, 7% strand	Q5NFG1

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	485	0.69	0.80	55	empty
2	161	0.43	0.75	25	empty
3	67	0.42	0.81	16	empty
4	100	0.42	0.77	19	empty
5	120	0.38	0.74	23	empty

Interfaces

1 interface between chains.

A–B · 952 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

4OMV · Crystal Structure of a Putative Macrophage Growth Locus, subunit A From Francisella… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5NFG1
Elsewhere: RCSB PDB 4OMV · PDBe 4OMV · UniProt Q5NFG1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.