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Crystal structure of a nitrate transporter
Analyse Crystal structure of a nitrate transporter in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4OH3
- Type
- protein
- Length
- 1,049 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nitrate transporter 1.1
- UniProt
- Q05085
- Ligands
- NO3
- Pockets
- 14 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 67% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nitrate transporter 1.1 | protein | 512 | 70% helix, 1% strand | Q05085 |
| B | Nitrate transporter 1.1 | protein | 537 | 65% helix, 3% strand | Q05085 |
Ligands and binding sites
- NO3 · Nitrate ion · ion · 2 copies · chains A, B
- LMT · Dodecyl-beta-D-maltoside · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 904 | 0.78 | 0.81 | 71 | NO3 |
| 2 | 1076 | 0.78 | 0.79 | 77 | NO3 |
| 3 | 327 | 0.77 | 0.88 | 25 | empty |
| 4 | 564 | 0.73 | 0.81 | 42 | empty |
| 5 | 311 | 0.54 | 0.75 | 39 | empty |
Interfaces
1 interface between chains.
- A–B · 1105 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q05085
- Elsewhere: RCSB PDB 4OH3 · PDBe 4OH3 · UniProt Q05085
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