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Crystal structure of the vaccine antigen transferrin binding protein B (tbpb) mutant tyr-95-ala from actinobacillus pleuropneumoniae H87

Analyse Crystal structure of the vaccine antigen transferrin binding protein B (tbpb)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4O3Z
Type: protein
Length: 500 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Outer membrane protein
UniProt: Q44167
Pockets: 5 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 51% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Outer membrane protein	protein	500	5% helix, 51% strand	Q44167

Ligands and binding sites

ACT · Acetate ion · additive · 5 copies · chains A
GOL · Glycerol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	148	0.48	0.77	28	ACT
2	146	0.45	0.76	25	empty
3	122	0.38	0.74	27	empty
4	84	0.33	0.74	19	empty
5	80	0.32	0.74	25	GOL

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4O3Z · Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q44167
Elsewhere: RCSB PDB 4O3Z · PDBe 4O3Z · UniProt Q44167

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