Research workbench

Crystal structure of the vaccine antigen transferrin binding protein B (tbpb) mutant arg-179-glu from actinobacillus pleuropneumoniae H87

Analyse Crystal structure of the vaccine antigen transferrin binding protein B (tbpb)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4O3Y
Type: protein
Length: 501 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Outer membrane protein
UniProt: Q44167
Pockets: 5 · best druggability 0.47

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 51% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Outer membrane protein	protein	501	5% helix, 51% strand	Q44167

Ligands and binding sites

ACT · Acetate ion · additive · 3 copies · chains A
GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	148	0.47	0.77	25	empty
2	124	0.45	0.78	24	ACT
3	98	0.37	0.75	17	ACT
4	107	0.36	0.74	20	empty
5	81	0.33	0.75	22	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4O3Y · Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q44167
Elsewhere: RCSB PDB 4O3Y · PDBe 4O3Y · UniProt Q44167

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.