Research workbench
Protein-L-isoaspartate O-methyltransferase from pyrobaculum aerophilum in complex with S-adenosyl-L-homocysteine
Analyse Protein-L-isoaspartate O-methyltransferase from pyrobaculum aerophilum in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4O29
- Type
- protein
- Length
- 207 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein-L-isoaspartate O-methyltransferase
- EC
- 2.1.1.77
- UniProt
- Q8ZYN0
- Ligands
- SAH
- Pockets
- 1 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) | protein | 207 | 32% helix, 31% strand | Q8ZYN0 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 151 | 0.69 | 0.89 | 31 | SAH |
Compared structures
- 4O29 · PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE from Pyrobaculum aerophilum in COMPLEX WITH… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8ZYN0 · AlphaFold monomer V2.0 prediction for protein-L-isoaspartate O-methyltransferase (Q8ZYN0) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZYN0
- Elsewhere: RCSB PDB 4O29 · PDBe 4O29 · UniProt Q8ZYN0
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