Research workbench
In-vivo crystallisation (midguts of a viviparous cockroach) and structure at 1.2 a resolution of a glycosylated, lipid-binding, lipocalin-like protein
Analyse In-vivo crystallisation (midguts of a viviparous cockroach) and structure at… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4NYQ
- Type
- protein
- Length
- 153 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Milk protein
- UniProt
- Q6SVB6
- Ligands
- OLA, EIC, NAG, BMA
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 10% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Milk protein | protein | 153 | 10% helix, 45% strand | Q6SVB6 |
Ligands and binding sites
- OLA · Oleic acid · ligand · chains A
- EIC · Linoleic acid · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 5 copies · chains A
- BMA · beta-D-mannopyranose · sugar
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 144 | 0.69 | 0.89 | 25 | OLA, EIC |
| 2 | 62 | 0.37 | 0.78 | 14 | GOL |
Modifications
Observed in the structure: 3 glycan, 2 disulfide (N-glycosylation, disulfide).
Compared structures
- 4NYQ · In-vivo crystallisation (midguts of a viviparous cockroach) and structure at 1.2 A… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6SVB6
- Elsewhere: RCSB PDB 4NYQ · PDBe 4NYQ · UniProt Q6SVB6
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