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Crystal structure of an organic hydroperoxide resistance protein from burkholderia cenocepacia
Analyse Crystal structure of an organic hydroperoxide resistance protein from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4NOZ
- Type
- protein
- Length
- 290 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Organic hydroperoxide resistance protein
- UniProt
- B4EPK2
- Pockets
- 3 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Organic hydroperoxide resistance protein | protein | 142 | 33% helix, 33% strand | B4EPK2 |
| B | Organic hydroperoxide resistance protein | protein | 148 | 32% helix, 32% strand | B4EPK2 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 7 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 237 | 0.66 | 0.83 | 29 | EDO |
| 2 | 234 | 0.64 | 0.82 | 30 | EDO |
| 3 | 73 | 0.34 | 0.76 | 16 | EDO |
Interfaces
1 interface between chains.
- A–B · 3339 Ų buried · 54 hydrogen bonds · protein-protein
Compared structures
- 4NOZ · Crystal Structure of an Organic Hydroperoxide Resistance Protein from Burkholderia… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4EPK2
- Elsewhere: RCSB PDB 4NOZ · PDBe 4NOZ · UniProt B4EPK2
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