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Crystal structure of the catalytic core of RRP6 from trypanosoma brucei
Analyse Crystal structure of the catalytic core of RRP6 from trypanosoma brucei in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4NLB
- Type
- protein
- Length
- 359 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosomal RNA processing protein 6
- UniProt
- Q581R8
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosomal RNA processing protein 6 | protein | 359 | 48% helix, 11% strand | Q581R8 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 304 | 0.67 | 0.82 | 36 | empty |
| 2 | 198 | 0.49 | 0.76 | 23 | empty |
| 3 | 131 | 0.36 | 0.72 | 26 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4NLB · Crystal structure of the catalytic core of RRP6 from Trypanosoma brucei · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q581R8
- Elsewhere: RCSB PDB 4NLB · PDBe 4NLB · UniProt Q581R8
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