Research workbench
Crystal structure of listeria monocytogenes hfq
Analyse Crystal structure of listeria monocytogenes hfq in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4NL2
- Type
- protein
- Length
- 440 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein hfq
- UniProt
- B8DG33
- Pockets
- 3 · best druggability 0.62
Structure
x-ray diffraction · 4 distinct chains · 20% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D, A, E | Protein hfq | protein | 73 | 21% helix, 44% strand | B8DG33 |
| B | Protein hfq | protein | 72 | 21% helix, 44% strand | B8DG33 |
| C | Protein hfq | protein | 74 | 20% helix, 43% strand | B8DG33 |
| F | Protein hfq | protein | 75 | 20% helix, 44% strand | B8DG33 |
Ligands and binding sites
- PGO · S-1,2-propanediol · additive · 7 copies · chains D, A, B, C, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 683 | 0.62 | 0.73 | 55 | empty |
| 2 | 68 | 0.36 | 0.78 | 17 | empty |
| 3 | 56 | 0.31 | 0.76 | 12 | PGO |
Interfaces
7 interfaces between chains.
- A–B · 892 Ų buried · 17 hydrogen bonds · protein-protein
- C–F · 879 Ų buried · 17 hydrogen bonds · protein-protein
- E–F · 864 Ų buried · 16 hydrogen bonds · protein-protein
- D–A · 861 Ų buried · 16 hydrogen bonds · protein-protein
- B–F · 348 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 4NL2 · Crystal Structure of Listeria monocytogenes Hfq · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B8DG33
- Elsewhere: RCSB PDB 4NL2 · PDBe 4NL2 · UniProt B8DG33
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.