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PB1 domain of ATARF7

Analyse PB1 domain of ATARF7 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4NJ6
Type: protein
Length: 1,387 residues
Chains: 16
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Auxin response factor 7
UniProt: P93022
Pockets: 20 · best druggability 0.84

Structure

x-ray diffraction · 11 distinct chains · 31% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, D, G	Auxin response factor 7	protein	88	30% helix, 27% strand	P93022
B, C, K	Auxin response factor 7	protein	89	34% helix, 30% strand	P93022
E	Auxin response factor 7	protein	85	29% helix, 24% strand	P93022
F	Auxin response factor 7	protein	89	30% helix, 24% strand	P93022
H, P	Auxin response factor 7	protein	87	31% helix, 23% strand	P93022
I	Auxin response factor 7	protein	86	29% helix, 26% strand	P93022
J	Auxin response factor 7	protein	82	30% helix, 27% strand	P93022
L	Auxin response factor 7	protein	84	31% helix, 24% strand	P93022
M	Auxin response factor 7	protein	88	33% helix, 24% strand	P93022
N	Auxin response factor 7	protein	82	30% helix, 26% strand	P93022
O	Auxin response factor 7	protein	86	35% helix, 24% strand	P93022

Pockets

20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	731	0.84	0.87	95	empty
2	1174	0.78	0.80	107	empty
3	712	0.71	0.78	62	empty
4	347	0.70	0.83	48	empty
5	451	0.67	0.79	66	empty

Interfaces

32 interfaces between chains.

B–L · 677 Å² buried · 10 hydrogen bonds · protein-protein
E–K · 621 Å² buried · 10 hydrogen bonds · protein-protein
C–G · 599 Å² buried · 10 hydrogen bonds · protein-protein
K–M · 570 Å² buried · 8 hydrogen bonds · protein-protein
C–I · 566 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

4NJ6 · PB1 Domain of AtARF7 · the same entry in another collection · chain I against I, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P93022
Elsewhere: RCSB PDB 4NJ6 · PDBe 4NJ6 · UniProt P93022

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