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Indole-3-glycerolphosphate synthase from sulfolobus solfataricus at 2.0 a resolution

Analyse Indole-3-glycerolphosphate synthase from sulfolobus solfataricus at 2.0 a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1IGS
Type: protein
Length: 247 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Indole-3-glycerolphosphate synthase
UniProt: Q06121
Ligands: PO4
Pockets: 1 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Indole-3-glycerolphosphate synthase	protein	247	42% helix, 17% strand	Q06121

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.73	0.91	29	PO4

Compared structures

1IGS · Indole-3-glycerolphosphate synthase from sulfolobus solfataricus at 2.0 a resolution · the same entry in another collection · chain A against A, TM-score 1.00
Q06121 · AlphaFold monomer V2.0 prediction for indole-3-glycerol phosphate synthase (Q06121) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q06121
Elsewhere: RCSB PDB 1IGS · PDBe 1IGS · UniProt Q06121

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