Research workbench
C-terminal domain of transcriptional repressor protein korb
Analyse C-terminal domain of transcriptional repressor protein korb in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1IGQ
- Type
- protein
- Length
- 227 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional repressor protein korb
- UniProt
- P07674
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 3 distinct chains · 5% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional repressor protein korb | protein | 54 | 6% helix, 54% strand | P07674 |
| B, C | Transcriptional repressor protein korb | protein | 57 | 5% helix, 51% strand | P07674 |
| D | Transcriptional repressor protein korb | protein | 59 | 5% helix, 53% strand | P07674 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 162 | 0.60 | 0.84 | 43 | empty |
| 2 | 98 | 0.34 | 0.73 | 20 | empty |
| 3 | 78 | 0.31 | 0.73 | 13 | empty |
Interfaces
5 interfaces between chains.
- B–D · 1024 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 893 Ų buried · 5 hydrogen bonds · protein-protein
- C–D · 428 Ų buried · 10 hydrogen bonds · protein-protein
- A–D · 204 Ų buried · 2 hydrogen bonds · protein-protein
- B–C · 195 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 1IGQ · C-terminal Domain of Transcriptional Repressor Protein KorB · the same entry in another collection · chain A against A, TM-score 1.00
- P07674 · AlphaFold monomer V2.0 prediction for transcriptional repressor protein korb (P07674) · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07674
- Elsewhere: RCSB PDB 1IGQ · PDBe 1IGQ · UniProt P07674
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