Research workbench
Three dimensional structure of an fv from a human IgM immunoglobulin
Analyse Three dimensional structure of an fv from a human IgM immunoglobulin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1IGM
- Type
- protein
- Length
- 244 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- IgM-kappa pot fv (light chain); IgM-kappa pot fv (heavy chain)
- Pockets
- 2 · best druggability 0.33
Structure
x-ray diffraction · 2 distinct chains · 4% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | IgM-kappa pot fv (light chain) | protein | 115 | 3% helix, 45% strand | — |
| H | IgM-kappa pot fv (heavy chain) | protein | 129 | 5% helix, 43% strand | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.33 | 0.74 | 18 | empty |
| 2 | 64 | 0.29 | 0.73 | 20 | empty |
Interfaces
1 interface between chains.
- L–H · 796 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1IGM · Three dimensional structure of an fv from a human IgM immunoglobulin · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1IGM · PDBe 1IGM
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