Research workbench
Cytochrome CD1 nitrite reductase, reduced form
Analyse Cytochrome CD1 nitrite reductase, reduced form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1AOF
- Type
- protein
- Length
- 1,074 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nitrite reductase
- UniProt
- P72181
- Ligands
- HEM, DHE, SO2
- Pockets
- 8 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 16% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nitrite reductase | protein | 532 | 15% helix, 38% strand | P72181 |
| B | Nitrite reductase | protein | 542 | 16% helix, 37% strand | P72181 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
- DHE · Heme D · ligand · 2 copies · chains A, B
- SO2 · Sulfur dioxide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.84 | 0.97 | 32 | empty |
| 2 | 549 | 0.77 | 0.84 | 57 | DHE, SO2 |
| 3 | 635 | 0.74 | 0.81 | 72 | DHE, SO2 |
| 4 | 916 | 0.74 | 0.78 | 61 | empty |
| 5 | 167 | 0.64 | 0.85 | 26 | HEM |
Interfaces
1 interface between chains.
- A–B · 1548 Ų buried · 31 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 cofactor (heme attachment).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P72181
- Elsewhere: RCSB PDB 1AOF · PDBe 1AOF · UniProt P72181
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.