Research workbench
Human steroid receptor RNA activator protein carboxy-terminal domain
Analyse Human steroid receptor RNA activator protein carboxy-terminal domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4NBO
- Type
- protein
- Length
- 204 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Steroid receptor RNA activator 1
- UniProt
- Q9HD15
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 80% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Steroid receptor RNA activator 1 | protein | 102 | 80% helix, 0% strand | Q9HD15 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 233 | 0.64 | 0.83 | 35 | empty |
| 2 | 57 | 0.33 | 0.77 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 533 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 4NBO · Human steroid receptor RNA activator protein carboxy-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HD15 · AlphaFold monomer V2.0 prediction for steroid receptor RNA activator 1 (Q9HD15) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HD15
- Elsewhere: RCSB PDB 4NBO · PDBe 4NBO · UniProt Q9HD15
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