Research workbench
The E254A mutant of the sodium bile acid symporter from yersinia frederiksenii
Analyse The E254A mutant of the sodium bile acid symporter from yersinia frederiksenii in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4N7X
- Type
- protein
- Length
- 306 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transporter, SODIUM/BILE acid symporter family
- UniProt
- C4ST46
- Pockets
- 4 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 84% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transporter, SODIUM/BILE acid symporter family | protein | 306 | 84% helix, 1% strand | C4ST46 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 383 | 0.69 | 0.81 | 50 | empty |
| 2 | 148 | 0.50 | 0.78 | 20 | empty |
| 3 | 128 | 0.45 | 0.77 | 18 | empty |
| 4 | 59 | 0.29 | 0.73 | 13 | empty |
Compared structures
- 4N7X · The E254A mutant of the sodium bile acid symporter from Yersinia frederiksenii · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C4ST46
- Elsewhere: RCSB PDB 4N7X · PDBe 4N7X · UniProt C4ST46
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