Research workbench
Crystal structure of eukaryotic thic from a. thaliana
Analyse Crystal structure of eukaryotic thic from a. thaliana in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4N7Q
- Type
- protein
- Length
- 472 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphomethylpyrimidine synthase, chloroplastic
- EC
- 4.1.99.17
- UniProt
- O82392
- Ligands
- CO
- Pockets
- 4 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphomethylpyrimidine synthase, chloroplastic (EC 4.1.99.17) | protein | 472 | 47% helix, 13% strand | O82392 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 394 | 0.72 | 0.83 | 51 | HEZ |
| 2 | 546 | 0.71 | 0.80 | 50 | CO |
| 3 | 98 | 0.53 | 0.83 | 24 | empty |
| 4 | 67 | 0.39 | 0.79 | 16 | empty |
Compared structures
- 4N7Q · Crystal structure of eukaryotic THIC from A. thaliana · the same entry in another collection · chain A against A, TM-score 1.00
- O82392 · AlphaFold monomer V2.0 prediction for phosphomethylpyrimidine synthase, chloroplastic… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O82392
- Elsewhere: RCSB PDB 4N7Q · PDBe 4N7Q · UniProt O82392
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