Research workbench

Crystal structure of eukaryotic translation initiation factor EIF5B (870-1116) from chaetomium thermophilum, domains III and IV

Analyse Crystal structure of eukaryotic translation initiation factor EIF5B (870-1116)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4N3G
Type: protein
Length: 247 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Eukaryotic translation initiation factor 5B-like protein, EIF5B(870-C)
UniProt: G0S8G9
Ligands: LAC, CL
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Eukaryotic translation initiation factor 5B-like protein, EIF5B(870-C)	protein	247	32% helix, 33% strand	G0S8G9

Ligands and binding sites

LAC · Lactic acid · ligand · 2 copies · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	76	0.36	0.76	14	empty

Compared structures

4N3G · Crystal structure of eukaryotic translation initiation factor eIF5B (870-1116) from… · the same entry in another collection · chain A against A, TM-score 1.00
G0S8G9 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 5B (G0S8G9) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0S8G9
Elsewhere: RCSB PDB 4N3G · PDBe 4N3G · UniProt G0S8G9

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.