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Structure of ricin a chain bound with benzyl-(2-(2-amino-4-oxo-3,4- dihydropteridine-7-CARBOXAMIDO)ETHYL)CARBAMATE

Analyse Structure of ricin a chain bound with benzyl-(2-(2-amino-4-oxo-3,4… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4MX5
Type: protein
Length: 263 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ricin a chain
EC: 3.2.2.22
UniProt: P02879
Ligands: 5MX
Pockets: 2 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Ricin a chain (EC 3.2.2.22)	protein	263	41% helix, 22% strand	P02879

Ligands and binding sites

5MX · benzyl (2-{[(2-amino-4-oxo-3,4-dihydropteridin-7-yl)carbonyl]amino}ethyl)carbamate · ligand · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	228	0.61	0.81	38	5MX
2	60	0.34	0.76	10	empty

Compared structures

4MX5 · Structure of ricin A chain bound with benzyl-(2-(2-amino-4-oxo-3,4-dihydropteridine-7-carb… · the same entry in another collection · chain X against X, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02879
Elsewhere: RCSB PDB 4MX5 · PDBe 4MX5 · UniProt P02879

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