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Crystal structure of closed inactive collybistin

Analyse Crystal structure of closed inactive collybistin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4MT6
Type
protein
Length
389 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Rho guanine nucleotide exchange factor 9
UniProt
Q9QX73
Pockets
4 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARho guanine nucleotide exchange factor 9protein38947% helix, 19% strandQ9QX73

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16830.710.7849empty
23480.590.7647empty
31160.410.7615empty
4500.290.7510empty

Compared structures

  • 4MT6 · Crystal structure of closed inactive collybistin · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9QX73 · AlphaFold monomer V2.0 prediction for rho guanine nucleotide exchange factor 9 (Q9QX73) · a predicted model of the same protein · chain A against A, TM-score 0.59

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