Research workbench
2.0A Crystal Structure of a Glutamate-1-Semialdehyde Aminotransferase from Yersinia pestis CO92
Analyse 2.0A Crystal Structure of a Glutamate-1-Semialdehyde Aminotransferase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4E77
- Type
- protein
- Length
- 406 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2
- Source
- Yersinia pestis
- Molecule
- Glutamate-1-semialdehyde 2,1-aminomutase
- EC
- 5.4.3.8
- UniProt
- A4TPW6
- Ligands
- NA, NO3
- Pockets
- 3 · best druggability 0.56
Structure
x-ray diffraction · resolution 2 · 1 distinct chain · 42% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) | protein | 406 | 42% helix, 17% strand | A4TPW6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 244 | 0.56 | 0.77 | 34 | empty |
| 2 | 225 | 0.52 | 0.77 | 26 | NO3 |
| 3 | 58 | 0.31 | 0.75 | 12 | empty |
Modifications
Observed in the structure: 17 modified (engineered).
Compared structures
- 4E77 · 2.0A crystal structure of a glutamate-1-semialdehyde aminotransferase from yersinia… · the same entry in another collection · chain A against A, TM-score 1.00
- A4TPW6 · AlphaFold monomer V2.0 prediction for glutamate-1-semialdehyde 2,1-aminomutase (A4TPW6) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4TPW6
- Elsewhere: RCSB PDB 4E77 · PDBe 4E77 · UniProt A4TPW6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.