Research workbench
Crystal structure of C.elegans PRMT7 in complex with SAH (P43212)
Analyse Crystal structure of C.elegans PRMT7 in complex with SAH (P43212) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3X0D
- Type
- protein
- Length
- 624 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.15
- Source
- Caenorhabditis elegans
- Molecule
- Protein arginine N-methyltransferase 7
- EC
- 2.1.1.-
- UniProt
- Q9XW42
- Ligands
- SAH, ZN
- Pockets
- 7 · best druggability 0.75
Structure
x-ray diffraction · resolution 2.15 · 1 distinct chain · 27% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein arginine N-methyltransferase 7 (EC 2.1.1.-) | protein | 624 | 27% helix, 30% strand | Q9XW42 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 848 | 0.75 | 0.79 | 89 | SAH |
| 2 | 172 | 0.66 | 0.86 | 24 | empty |
| 3 | 67 | 0.65 | 0.93 | 28 | empty |
| 4 | 134 | 0.57 | 0.83 | 22 | empty |
| 5 | 77 | 0.50 | 0.83 | 15 | empty |
Compared structures
- 3X0D · Crystal structure of C.ELEGANS PRMT7 in complex with sah (P43212) · the same entry in another collection · chain A against A, TM-score 1.00
- Q9XW42 · AlphaFold monomer V2.0 prediction for protein arginine N-methyltransferase 7 (Q9XW42) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9XW42
- Elsewhere: RCSB PDB 3X0D · PDBe 3X0D · UniProt Q9XW42
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