Research workbench
Crystal structure of lambda repressor (1-45) fused with maltose-binding protein
Analyse Crystal structure of lambda repressor (1-45) fused with maltose-binding protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3WOA
- Type
- protein
- Length
- 413 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2
- Source
- Enterobacteria phage lambda; Escherichia coli
- Molecule
- Repressor protein CI, Maltose-binding periplasmic protein
- UniProt
- P03034, P0AEX9
- Ligands
- GLC
- Pockets
- 3 · best druggability 0.69
Structure
x-ray diffraction · resolution 2 · 1 distinct chain · 46% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Repressor protein CI, Maltose-binding periplasmic protein | protein | 413 | 46% helix, 19% strand | P03034, P0AEX9 |
Ligands and binding sites
- GLC · alpha-D-glucopyranose · sugar · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 321 | 0.69 | 0.83 | 34 | GLC |
| 2 | 131 | 0.39 | 0.74 | 21 | empty |
| 3 | 51 | 0.33 | 0.78 | 13 | empty |
Compared structures
- 3WOA · Crystal structure of lambda repressor (1-45) fused with maltose- binding protein · the same entry in another collection · chain A against A, TM-score 1.00
- P0AEX9 · AlphaFold monomer V2.0 prediction for MALTOSE/MALTODEXTRIN-binding periplasmic protein… · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03034
- Every structure of UniProt P0AEX9
- Elsewhere: RCSB PDB 3WOA · PDBe 3WOA · UniProt P03034 · UniProt P0AEX9
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