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Crystal structure of the C-terminal domain of Themus thermophilus LitR in complex with cobalamin

Analyse Crystal structure of the C-terminal domain of Themus thermophilus LitR in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3WHP
Type: protein
Length: 192 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.52
Source: Thermus thermophilus
Molecule: Probable transcriptional regulator
UniProt: Q746J7
Ligands: B12
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · resolution 2.52 · 1 distinct chain · 54% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable transcriptional regulator	protein	192	54% helix, 10% strand	Q746J7

Ligands and binding sites

B12 · Cobalamin · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	274	0.63	0.81	39	B12

Compared structures

3WHP · Crystal structure of the C-terminal domain of themus thermophilus litr in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q746J7
Elsewhere: RCSB PDB 3WHP · PDBe 3WHP · UniProt Q746J7

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