Research workbench
Structural insights into thioredoxin-2: a component of malaria parasite protein secretion machinery
Analyse Structural insights into thioredoxin-2: a component of malaria parasite protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3UL3
- Type
- protein
- Length
- 206 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.905
- Source
- Plasmodium falciparum
- Molecule
- Thioredoxin
- UniProt
- Q8IDP4
- Pockets
- 2 · best druggability 0.79
Structure
x-ray diffraction · resolution 2.905 · 1 distinct chain · 36% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A | Thioredoxin | protein | 103 | 36% helix, 26% strand | Q8IDP4 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 932 | 0.79 | 0.81 | 87 | empty |
| 2 | 94 | 0.45 | 0.80 | 26 | empty |
Interfaces
1 interface between chains.
- B–A · 728 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 3UL3 · Structural insights into thioredoxin-2: a component of malaria parasite protein secretion… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IDP4
- Elsewhere: RCSB PDB 3UL3 · PDBe 3UL3 · UniProt Q8IDP4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.