Research workbench
Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) from Homo sapiens (Human), Northeast Structural Genomics Consortium target id HR5562A
Analyse Crystal Structure of a domain of Brefeldin A-inhibited guanine… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3SWV
- Type
- protein
- Length
- 188 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3
- Source
- Homo sapiens
- Molecule
- Brefeldin A-inhibited guanine nucleotide-exchange protein 2
- UniProt
- Q9Y6D5
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · resolution 3 · 1 distinct chain · 47% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | protein | 188 | 47% helix, 0% strand | Q9Y6D5 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.31 | 0.75 | 10 | empty |
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 3SWV · Crystal structure of a domain of brefeldin a-inhibited guanine nucleotide-exchange… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y6D5 · AlphaFold monomer V2.0 prediction for brefeldin a-inhibited guanine nucleotide-exchange… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y6D5
- Elsewhere: RCSB PDB 3SWV · PDBe 3SWV · UniProt Q9Y6D5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.