Research workbench
Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150
Analyse Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3S6B
- Type
- protein
- Length
- 345 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.95
- Source
- Plasmodium falciparum
- Molecule
- Methionine aminopeptidase
- EC
- 3.4.11.18
- UniProt
- Q8IJP2
- Ligands
- FE
- Pockets
- 4 · best druggability 0.57
Structure
x-ray diffraction · resolution 1.95 · 1 distinct chain · 29% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methionine aminopeptidase (EC 3.4.11.18) | protein | 345 | 29% helix, 21% strand | Q8IJP2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 179 | 0.57 | 0.81 | 29 | empty |
| 2 | 54 | 0.43 | 0.83 | 13 | empty |
| 3 | 60 | 0.26 | 0.72 | 19 | empty |
| 4 | 55 | 0.25 | 0.72 | 20 | empty |
Compared structures
- 3S6B · Crystal structure of methionine aminopeptidase 1B from plasmodium falciparum, PF10_0150 · the same entry in another collection · chain A against A, TM-score 1.00
- Q8IJP2 · AlphaFold monomer V2.0 prediction for methionine aminopeptidase 1B (Q8IJP2) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IJP2
- Elsewhere: RCSB PDB 3S6B · PDBe 3S6B · UniProt Q8IJP2
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