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Crystal structure of an HIT-like protein from mycobacterium paratuberculosis

Analyse Crystal structure of an HIT-like protein from mycobacterium paratuberculosis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3P0T
Type: protein
Length: 272 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.9
Source: Mycobacterium avium subsp. paratuberculosis
Molecule: Uncharacterized protein
UniProt: Q743J2
Ligands: SO4
Pockets: 1 · best druggability 0.68

Structure

x-ray diffraction · resolution 1.9 · 1 distinct chain · 40% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Uncharacterized protein	protein	136	40% helix, 19% strand	Q743J2

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A, B
EDO · 1,2-ethanediol · additive · 8 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.68	0.95	19	EDO

Interfaces

1 interface between chains.

A–B · 1512 Å² buried · 23 hydrogen bonds · protein-protein

Compared structures

3P0T · Crystal structure of an hit-like protein from mycobacterium paratuberculosis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q743J2
Elsewhere: RCSB PDB 3P0T · PDBe 3P0T · UniProt Q743J2

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