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Effector binding Domain of LysR-Type transcription factor RovM from Y. pseudotuberculosis

Analyse Effector binding Domain of LysR-Type transcription factor RovM from Y.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ONM
Type: protein
Length: 370 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.4
Source: Yersinia pseudotuberculosis
Molecule: Transcriptional regulator LrhA
UniProt: A7FGQ3
Pockets: 6 · best druggability 0.60

Structure

x-ray diffraction · resolution 2.4 · 2 distinct chains · 32% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator LrhA	protein	190	34% helix, 29% strand	A7FGQ3
B	Transcriptional regulator LrhA	protein	180	30% helix, 31% strand	A7FGQ3

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	413	0.60	0.76	50	empty
2	262	0.57	0.77	30	empty
3	56	0.56	0.90	22	empty
4	136	0.56	0.83	25	empty
5	53	0.35	0.79	14	empty

Interfaces

1 interface between chains.

A–B · 899 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

3ONM · Effector binding domain of lysr-type transcription factor rovm from Y. pseudotuberculosis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A7FGQ3
Elsewhere: RCSB PDB 3ONM · PDBe 3ONM · UniProt A7FGQ3

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