Research workbench
Crystal structure of the human 70kDa heat shock protein 1-like ATPase domain in complex with ADP and inorganic phosphate
Analyse Crystal structure of the human 70kDa heat shock protein 1-like ATPase domain in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3GDQ
- Type
- protein
- Length
- 376 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.8
- Source
- Homo sapiens
- Molecule
- Heat shock 70 kDa protein 1-like
- UniProt
- P34931
- Ligands
- ADP, MN, PO4
- Pockets
- 1 · best druggability 0.77
Structure
x-ray diffraction · resolution 1.8 · 1 distinct chain · 42% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat shock 70 kDa protein 1-like | protein | 376 | 42% helix, 29% strand | P34931 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- MN · Manganese (II) ion · metal · chains A
- PO4 · Phosphate ion · ion · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 634 | 0.77 | 0.83 | 72 | PO4, ADP, MN |
Compared structures
- 3GDQ · Crystal structure of the human 70KDA heat shock protein 1-like ATPase domain in complex… · the same entry in another collection · chain A against A, TM-score 1.00
- P34931 · AlphaFold monomer V2.0 prediction for heat shock 70 kda protein 1-like (P34931) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P34931
- Elsewhere: RCSB PDB 3GDQ · PDBe 3GDQ · UniProt P34931
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