Research workbench
Native fungus laccase from Trametes hirsuta
Analyse Native fungus laccase from Trametes hirsuta in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3FPX
- Type
- protein
- Length
- 499 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.8
- Source
- Trametes hirsuta
- Molecule
- Laccase
- EC
- 1.10.3.2
- UniProt
- B2L9C1
- Ligands
- NAG, MAN, BMA, CU, PO4
- Pockets
- 4 · best druggability 0.54
Structure
x-ray diffraction · resolution 1.8 · 1 distinct chain · 11% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Laccase (EC 1.10.3.2) | protein | 499 | 11% helix, 38% strand | B2L9C1 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 7 copies · chains A
- MAN · alpha-D-mannopyranose · sugar · 4 copies · chains A
- BMA · beta-D-mannopyranose · sugar · 2 copies · chains A
- CU · Copper (II) ion · metal · 4 copies · chains A
- PO4 · Phosphate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 119 | 0.54 | 0.82 | 20 | empty |
| 2 | 255 | 0.51 | 0.75 | 32 | empty |
| 3 | 84 | 0.42 | 0.79 | 22 | empty |
| 4 | 110 | 0.38 | 0.75 | 18 | empty |
Modifications
Observed in the structure: 4 glycan, 2 disulfide (N-glycosylation, disulfide).
Compared structures
- 3FPX · Native fungus laccase from trametes hirsuta · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2L9C1
- Elsewhere: RCSB PDB 3FPX · PDBe 3FPX · UniProt B2L9C1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.