Research workbench
Structural and Functional Characterization of TRI3 Trichothecene 15-O-acetyltransferase from Fusarium sporotrichioides
Analyse Structural and Functional Characterization of TRI3 Trichothecene… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3FP0
- Type
- protein
- Length
- 511 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.9
- Source
- Fusarium sporotrichioides
- Molecule
- 15-O-acetyltransferase
- UniProt
- Q9C1B7
- Ligands
- FP0, GLC, Z9N
- Pockets
- 6 · best druggability 0.80
Structure
x-ray diffraction · resolution 1.9 · 1 distinct chain · 41% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 15-O-acetyltransferase | protein | 511 | 41% helix, 22% strand | Q9C1B7 |
Ligands and binding sites
- FP0 · (3alpha)-15-hydroxy-12,13-epoxytrichothec-9-en-3-yl acetate · ligand · chains A
- GLC · alpha-D-glucopyranose · sugar · chains A
- Z9N · alpha-D-fructofuranose · sugar · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 575 | 0.80 | 0.86 | 69 | FP0 |
| 2 | 165 | 0.48 | 0.77 | 31 | empty |
| 3 | 129 | 0.43 | 0.76 | 22 | empty |
| 4 | 80 | 0.32 | 0.74 | 23 | empty |
| 5 | 56 | 0.31 | 0.75 | 17 | empty |
Compared structures
- 3FP0 · Structural and functional characterization of TRI3 trichothecene 15-O- acetyltransferase… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9C1B7 · AlphaFold monomer V2.0 prediction for trichothecene 15-O-acetyltransferase TRI3 (Q9C1B7) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9C1B7
- Elsewhere: RCSB PDB 3FP0 · PDBe 3FP0 · UniProt Q9C1B7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.