Research workbench

Crystal structure of the bovine lipoyltransferase in its unliganded form

Analyse Crystal structure of the bovine lipoyltransferase in its unliganded form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3A7U
Type: protein
Length: 325 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.44
Source: Bos taurus
Molecule: Lipoyltransferase 1, mitochondrial
EC: 2.3.1.-
UniProt: O46419
Pockets: 3 · best druggability 0.47

Structure

x-ray diffraction · resolution 3.44 · 1 distinct chain · 31% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lipoyltransferase 1, mitochondrial (EC 2.3.1.-)	protein	325	31% helix, 26% strand	O46419

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	156	0.47	0.76	35	empty
2	116	0.44	0.78	22	empty
3	55	0.44	0.83	19	empty

Compared structures

3A7U · Crystal structure of the bovine lipoyltransferase in its unliganded form · the same entry in another collection · chain A against A, TM-score 1.00
O46419 · AlphaFold monomer V2.0 prediction for lipoyltransferase 1, mitochondrial (O46419) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O46419
Elsewhere: RCSB PDB 3A7U · PDBe 3A7U · UniProt O46419

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.