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Crystal structure of dimeric form of PfFabZ in crystal form2

Analyse Crystal structure of dimeric form of PfFabZ in crystal form2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2OKI
Type: protein
Length: 244 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.7
Source: Plasmodium falciparum
Molecule: Beta-hydroxyacyl-ACP dehydratase
EC: 4.2.1.60
UniProt: Q965D7
Pockets: 3 · best druggability 0.69

Structure

x-ray diffraction · resolution 2.7 · 2 distinct chains · 14% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-hydroxyacyl-ACP dehydratase (EC 4.2.1.60)	protein	126	13% helix, 44% strand	Q965D7
B	Beta-hydroxyacyl-ACP dehydratase (EC 4.2.1.60)	protein	118	14% helix, 45% strand	Q965D7

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	216	0.69	0.86	38	empty
2	135	0.59	0.84	25	empty
3	84	0.39	0.77	14	empty

Interfaces

1 interface between chains.

A–B · 974 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

2OKI · Crystal structure of dimeric form of pffabz in crystal FORM2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q965D7
Elsewhere: RCSB PDB 2OKI · PDBe 2OKI · UniProt Q965D7

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