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MoeA S371W

Analyse MoeA S371W in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2NRS
Type: protein
Length: 806 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.8
Source: Escherichia coli
Molecule: Molybdopterin biosynthesis protein moeA
UniProt: P12281
Pockets: 9 · best druggability 0.80

Structure

x-ray diffraction · resolution 2.8 · 1 distinct chain · 21% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Molybdopterin biosynthesis protein moeA	protein	403	21% helix, 31% strand	P12281

Pockets

9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1024	0.80	0.81	90	empty
2	1197	0.79	0.81	95	empty
3	657	0.69	0.77	48	empty
4	156	0.60	0.84	18	empty
5	98	0.43	0.78	14	empty

Interfaces

1 interface between chains.

A–B · 2463 Å² buried · 21 hydrogen bonds · protein-protein

Compared structures

2NRS · MOEA S371W · the same entry in another collection · chain A against A, TM-score 1.00
P12281 · AlphaFold monomer V2.0 prediction for molybdopterin molybdenumtransferase (P12281) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P12281
Elsewhere: RCSB PDB 2NRS · PDBe 2NRS · UniProt P12281

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