Research workbench
Solution structure of the 2A proteinase from a common cold agent, human rhinovirus RV-C02, strain W12
Analyse Solution structure of the 2A proteinase from a common cold agent, human… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2M5T
- Type
- protein
- Length
- 142 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- NOT
- Source
- Rhinovirus C
- Molecule
- human rhinovirus 2A proteinase
- UniProt
- I2CMJ2
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.61
Structure
solution nmr · resolution NOT · 1 distinct chain · 2% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | human rhinovirus 2A proteinase | protein | 142 | 2% helix, 40% strand | I2CMJ2 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 229 | 0.61 | 0.81 | 36 | empty |
| 2 | 184 | 0.60 | 0.82 | 35 | empty |
Compared structures
- 2M5T · Solution structure of the 2A proteinase from a common cold agent, human rhinovirus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I2CMJ2
- Elsewhere: RCSB PDB 2M5T · PDBe 2M5T · UniProt I2CMJ2
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