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The membran-proximal domain of ADAM17

Analyse The membran-proximal domain of ADAM17 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2M2F
Type: protein
Length: 62 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: NOT
Source: Homo sapiens
Molecule: Disintegrin and metalloproteinase domain-containing protein 17
EC: 3.4.24.86
UniProt: P78536

Structure

solution nmr · resolution NOT · 1 distinct chain · 13% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Disintegrin and metalloproteinase domain-containing protein 17 (EC 3.4.24.86)	protein	62	13% helix, 29% strand	P78536

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

2M2F · The membran-proximal domain of ADAM17 · the same entry in another collection · chain A against A, TM-score 1.00
P78536 · AlphaFold monomer V2.0 prediction for disintegrin and metalloproteinase domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P78536
Elsewhere: RCSB PDB 2M2F · PDBe 2M2F · UniProt P78536

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