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Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA

Analyse Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2LOA
Type
DNA
Length
10 nucleotides
Chains
1
Method
solution nmr
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
NOT
Molecule
DNA (5'-D(*GP*CP*CP*GP*CP*AP*GP*TP*GP*C)-3')
Ligands
C4Q, ZN

Structure

solution nmr · resolution NOT · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'-D(*GP*CP*CP*GP*CP*AP*GP*TP*GP*C)-3')dna10——

Ligands and binding sites

  • C4Q · 4-(1,4,7,10-tetraazacyclododecan-1-ylmethyl)quinoline · ligand · chains A
  • ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 2LOA · Structural basis for bifunctional ZN(II) macrocyclic complex recognition of thymine… · the same entry in another collection · chain A against A, TM-score 1.00

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