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NMR structure of gamma herpesvirus 68 a viral Bcl-2 homolog

Analyse NMR structure of gamma herpesvirus 68 a viral Bcl-2 homolog in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2ABO
Type
protein
Length
131 residues
Chains
1
Method
solution nmr
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
NOT
Source
Murid herpesvirus 4
Molecule
bcl-2 homolog
UniProt
P89884
Pockets
1 · best druggability 0.40

Structure

solution nmr · resolution NOT · 1 distinct chain · 57% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
Abcl-2 homologprotein13157% helix, 0% strandP89884

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1780.400.7816empty

Compared structures

  • 2ABO · NMR structure of gamma herpesvirus 68 a viral BCL-2 homolog · the same entry in another collection · chain A against A, TM-score 1.00

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