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Crystal structure of the quorum-sensing protein TraM from Agrobacterium tumefaciens at 1.65 Ang. resolution

Analyse Crystal structure of the quorum-sensing protein TraM from Agrobacterium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1US6
Type
protein
Length
189 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
1.65
Source
AGROBACTERIUM TUMEFACIENS
Molecule
Transcriptional repressor tram
UniProt
Q57471
Pockets
1 · best druggability 0.61

Structure

x-ray diffraction · resolution 1.65 · 2 distinct chains · 69% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATranscriptional repressor tramprotein9072% helix, 0% strandQ57471
BTranscriptional repressor tramprotein9966% helix, 5% strandQ57471

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12340.610.8130empty

Interfaces

1 interface between chains.

  • A–B · 1087 Ų buried · 2 hydrogen bonds · protein-protein

Compared structures

  • 1US6 · Crystal structure of the quorum-sensing protein tram from agrobacterium tumefaciens at… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q57471 · AlphaFold monomer V2.0 prediction for transcriptional repressor tram (Q57471) · a predicted model of the same protein · chain A against A, TM-score 0.96

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