Research workbench
8T8P: 33-mer FliF MS-ring from Salmonella
Analyse 8T8P: 33-mer FliF MS-ring from Salmonella in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 8T8P
- Type
- protein
- Length
- 9,009 residues
- Chains
- 33
- Method
- electron microscopy
- Authors
- Singh, P.K., Iverson, T.M.
- Deposited
- 06/23/23
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.4
- Source
- Salmonella enterica subsp. enterica serovar Typhimurium
- Molecule
- Flagellar M-ring protein
- UniProt
- P15928
- Pockets
- 20 · best druggability 0.83
Structure
electron microscopy · resolution 3.4 · 2 distinct chains · 32% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, D, F, G, I, J, L, M, O, P, R, S, V, W, Y, Z, BA, CA, EA, FA, HA | Flagellar M-ring protein | protein | 254 | 30% helix, 32% strand | P15928 |
| B, E, H, K, N, Q, T, X, AA, DA, GA | Flagellar M-ring protein | protein | 311 | 34% helix, 26% strand | P15928 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 855 | 0.83 | 0.86 | 126 | empty |
| 2 | 866 | 0.81 | 0.84 | 132 | empty |
| 3 | 927 | 0.80 | 0.82 | 100 | empty |
| 4 | 973 | 0.80 | 0.82 | 105 | empty |
| 5 | 891 | 0.79 | 0.82 | 93 | empty |
Interfaces
44 interfaces between chains.
- C–FA · 3555 Ų buried · 58 hydrogen bonds · protein-protein
- D–I · 3541 Ų buried · 61 hydrogen bonds · protein-protein
- Z–EA · 3540 Ų buried · 58 hydrogen bonds · protein-protein
- CA–HA · 3536 Ų buried · 59 hydrogen bonds · protein-protein
- J–O · 3528 Ų buried · 58 hydrogen bonds · protein-protein
Compared structures
- P15928 · AlphaFold monomer V2.0 prediction for flagellar M-ring protein (P15928) · a predicted model of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15928
- Elsewhere: RCSB PDB 8T8P · PDBe 8T8P · UniProt P15928
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.