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Crystal structure of a strain-transcending single-component Plasmodium falciparum AMA1-RON2L structure-based design immunogen 1 (SBD1)
Analyse Crystal structure of a strain-transcending single-component Plasmodium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 8GID
- Type
- protein
- Length
- 339 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.8
- Source
- Plasmodium falciparum 3D7
- Molecule
- Apical membrane antigen 1, rhoptry neck protein 2 chimera
- UniProt
- D9MXR5, Q7KQK5, Q8IKV6
- Pockets
- 2 · best druggability 0.57
Structure
x-ray diffraction · resolution 1.8 · 1 distinct chain · 17% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Apical membrane antigen 1, rhoptry neck protein 2 chimera | protein | 339 | 17% helix, 27% strand | D9MXR5, Q7KQK5, Q8IKV6 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 132 | 0.57 | 0.83 | 30 | empty |
| 2 | 60 | 0.30 | 0.76 | 12 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D9MXR5
- Every structure of UniProt Q7KQK5
- Every structure of UniProt Q8IKV6
- Elsewhere: RCSB PDB 8GID · PDBe 8GID · UniProt D9MXR5 · UniProt Q7KQK5 · UniProt Q8IKV6
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