Research workbench

Crystal structure of human Sar1bE140D

Analyse Crystal structure of human Sar1bE140D in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 8E0D
Type: protein
Length: 182 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.981
Source: Homo sapiens
Molecule: GTP-binding protein SAR1b
UniProt: Q9Y6B6
Ligands: G4P
Pockets: 1 · best druggability 0.28

Structure

x-ray diffraction · resolution 1.981 · 1 distinct chain · 29% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GTP-binding protein SAR1b	protein	182	29% helix, 22% strand	Q9Y6B6

Ligands and binding sites

G4P · Guanosine-5',3'-tetraphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.28	0.75	15	empty

Compared structures

Q9Y6B6 · AlphaFold monomer V2.0 prediction for GTP-binding protein SAR1B (Q9Y6B6) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y6B6
Elsewhere: RCSB PDB 8E0D · PDBe 8E0D · UniProt Q9Y6B6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.