Research workbench
Structure of the disulfide-locked substrate binding protein HiSiaP.
Analyse Structure of the disulfide-locked substrate binding protein HiSiaP. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 8CP7
- Type
- protein
- Length
- 310 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.9
- Source
- Haemophilus influenzae
- Molecule
- Sialic acid-binding periplasmic protein SiaP
- UniProt
- P44542
- Ligands
- SLB, ZN
- Pockets
- 1 · best druggability 0.81
Structure
x-ray diffraction · resolution 1.9 · 1 distinct chain · 52% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sialic acid-binding periplasmic protein SiaP | protein | 310 | 52% helix, 19% strand | P44542 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 219 | 0.81 | 0.94 | 46 | SLB |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- P44542 · AlphaFold monomer V2.0 prediction for sialic acid-binding periplasmic protein siap… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P44542
- Elsewhere: RCSB PDB 8CP7 · PDBe 8CP7 · UniProt P44542
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.