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Escherichia coli periplasmic phytase AppA D304A,T305E mutant, complex with myo-inositol hexakissulfate
Analyse Escherichia coli periplasmic phytase AppA D304A,T305E mutant, complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7Z2W
- Type
- protein
- Length
- 406 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.42
- Source
- Escherichia coli
- Molecule
- Acidphosphatase
- EC
- 3.1.3.26, 3.1.3.2
- UniProt
- G0ZGJ8
- Ligands
- IHS, PO4
- Pockets
- 2 · best druggability 0.65
Structure
x-ray diffraction · resolution 1.42 · 1 distinct chain · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Acidphosphatase (EC 3.1.3.26, 3.1.3.2) | protein | 406 | 45% helix, 15% strand | G0ZGJ8 |
Ligands and binding sites
- IHS · D-myo-inositol-hexasulphate · ligand · chains A
- PO4 · Phosphate ion · ion · chains A
- GOL · Glycerol · additive · chains A
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 458 | 0.65 | 0.78 | 41 | IHS |
| 2 | 53 | 0.39 | 0.81 | 10 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 7Z2W · Escherichia COLI periplasmic phytase appa D304A,T305E mutant, complex with myo-inositol… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0ZGJ8
- Elsewhere: RCSB PDB 7Z2W · PDBe 7Z2W · UniProt G0ZGJ8
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