Research workbench
Crystal structure of Adenosine triphosphate phosphoribosyltransferase (HisG) from Acinetobacter baumannii at 2.975 A resolution
Analyse Crystal structure of Adenosine triphosphate phosphoribosyltransferase (HisG)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7WZY
- Type
- protein
- Length
- 454 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.975
- Source
- Acinetobacter baumannii
- Molecule
- ATP phosphoribosyltransferase
- EC
- 2.4.2.17
- UniProt
- V5VGC6
- Pockets
- 5 · best druggability 0.68
Structure
x-ray diffraction · resolution 2.975 · 1 distinct chain · 28% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ATP phosphoribosyltransferase (EC 2.4.2.17) | protein | 227 | 28% helix, 29% strand | V5VGC6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 584 | 0.68 | 0.78 | 55 | empty |
| 2 | 468 | 0.65 | 0.78 | 49 | empty |
| 3 | 120 | 0.50 | 0.80 | 22 | empty |
| 4 | 113 | 0.41 | 0.76 | 18 | empty |
| 5 | 70 | 0.32 | 0.76 | 16 | FMT |
Interfaces
1 interface between chains.
- A–B · 1477 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 7WZY · Crystal structure of adenosine triphosphate phosphoribosyltransferase (hisg) from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt V5VGC6
- Elsewhere: RCSB PDB 7WZY · PDBe 7WZY · UniProt V5VGC6
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