Research workbench
Crystal structure of fast switching M159E mutant of fluorescent protein Dronpa (Dronpa2)
Analyse Crystal structure of fast switching M159E mutant of fluorescent protein Dronpa… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7RRK
- Type
- protein
- Length
- 1,719 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.929
- Source
- Echinophyllia sp. SC22
- Molecule
- Fluorescent protein Dronpa
- UniProt
- Q5TLG6
- Pockets
- 20 · best druggability 0.83
Structure
x-ray diffraction · resolution 1.929 · 5 distinct chains · 4% helix, 57% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fluorescent protein Dronpa | protein | 214 | 4% helix, 58% strand | Q5TLG6 |
| B | Fluorescent protein Dronpa | protein | 220 | 4% helix, 56% strand | Q5TLG6 |
| C, D, E, F | Fluorescent protein Dronpa | protein | 213 | 4% helix, 58% strand | Q5TLG6 |
| G | Fluorescent protein Dronpa | protein | 212 | 4% helix, 58% strand | Q5TLG6 |
| H | Fluorescent protein Dronpa | protein | 221 | 4% helix, 56% strand | Q5TLG6 |
Pockets
20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1074 | 0.83 | 0.84 | 102 | empty |
| 2 | 1185 | 0.83 | 0.84 | 104 | empty |
| 3 | 89 | 0.76 | 0.98 | 23 | empty |
| 4 | 75 | 0.76 | 0.99 | 24 | empty |
| 5 | 85 | 0.76 | 0.98 | 23 | empty |
Interfaces
11 interfaces between chains.
- A–E · 1303 Ų buried · 27 hydrogen bonds · protein-protein
- B–F · 1264 Ų buried · 22 hydrogen bonds · protein-protein
- C–G · 1259 Ų buried · 21 hydrogen bonds · protein-protein
- D–H · 1254 Ų buried · 21 hydrogen bonds · protein-protein
- C–E · 890 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 7RRK · Crystal structure of fast switching M159E mutant of fluorescent protein dronpa (DRONPA2) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5TLG6
- Elsewhere: RCSB PDB 7RRK · PDBe 7RRK · UniProt Q5TLG6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.