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mosquitocidal Cry11Aa-F17Y determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography

Analyse mosquitocidal Cry11Aa-F17Y determined at pH 7 from naturally-occurring… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7QX7
Type: protein
Length: 630 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.4
Source: Bacillus thuringiensis serovar israelensis
Molecule: Pesticidal crystal protein Cry11Aa
UniProt: P21256
Pockets: 6 · best druggability 0.66

Structure

x-ray diffraction · resolution 3.4 · 1 distinct chain · 31% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pesticidal crystal protein Cry11Aa	protein	630	31% helix, 28% strand	P21256

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	217	0.66	0.84	25	empty
2	181	0.64	0.85	33	empty
3	298	0.62	0.79	30	empty
4	171	0.57	0.81	25	empty
5	103	0.39	0.76	22	empty

Compared structures

7QX7 · Mosquitocidal CRY11AA-F17Y determined at pH 7 from naturally-occurring nanocrystals by… · the same entry in another collection · chain A against A, TM-score 1.00
P21256 · AlphaFold monomer V2.0 prediction for pesticidal crystal protein CRY11AA (P21256) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21256
Elsewhere: RCSB PDB 7QX7 · PDBe 7QX7 · UniProt P21256

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