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Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to parallel quadruplex-duplex (Q-D) hybrid
Analyse Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7PNG
- Type
- DNA
- Length
- 36 nucleotides
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- NOT
- Source
- synthetic construct
- Molecule
- DNA (37-mer)
- Ligands
- 7V5
- Pockets
- 1 · best druggability 0.29
Structure
solution nmr · resolution NOT · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA (37-mer) | dna | 36 | — | — |
Ligands and binding sites
- 7V5 · ~{N}-(5~{H}-indolo[3,2-b]quinolin-11-yl)-~{N}',~{N}'-dimethyl-propane-1,3-diamine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.29 | 0.75 | 8 | 7V5 |
Modifications
Observed in the structure: 1 modified (nucleotide modification).
Compared structures
- 7PNG · Solution structure of 1:1 complex of an indoloquinoline derivative syuiq-5 to parallel… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7PNG · PDBe 7PNG
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