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PanDDA analysis group deposition -- PHIP in complex with Z1004277578

Analyse PanDDA analysis group deposition -- PHIP in complex with Z1004277578 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7FVP
Type: protein
Length: 121 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.15
Source: Homo sapiens
Molecule: PH-interacting protein
UniProt: Q8WWQ0
Ligands: ZQ0
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · resolution 1.15 · 1 distinct chain · 68% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PH-interacting protein	protein	121	68% helix, 0% strand	Q8WWQ0

Ligands and binding sites

ZQ0 · N-butyl-4-(5-methylfuran-2-carbonyl)piperazine-1-carboxamide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	125	0.55	0.83	22	ZQ0

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WWQ0
Elsewhere: RCSB PDB 7FVP · PDBe 7FVP · UniProt Q8WWQ0

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